The inflammatory reaction is the contribution of the cells in the process of tissue repair20. There were signs of inflammation in the animals receiving the spongy film of polysaccharide higher placement than those not receiving in the control group. At the experimental group we observed the formation of an inflammatory process at the expense of polymorphonuclear cells with the presence of epithelial hyperplasia in D3 from the treatment, observing a clutter cellular from D3 to the last day of follow-up (D11) in control group. Regarding to the macroscopic observation, it was found that the experimental group, in an initial phases the opened wound, peripheral vascular irrigation with fibrin and presence of polysaccharide film.