It has been shown that ATZ tends to be sequestrated in natural
soil environment [18,19], but the underlying mechanisms by
which ATZ binds to SOM remain largely unexplored. This is the first
research that demonstrates nucleophilic substitution could be an
important mechanism and sulfur-containing amino acids/peptides
play a critical role as the nucleophile. We conceive this process
would diminish xenobiotic transport, bioavailability, and toxicity
[33]. Understanding such mechanisms and governing factors is of
great importance to accurately predict the environmental behavior
of ATZ, making scientific environmental risk assessment possible.
On the other hand, mechanistic understanding of ATZ sequestion
may catalyze novel ideas to mitigate ATZ contamination by taking
advantage of such processes in management and/or remediation
programs
It has been shown that ATZ tends to be sequestrated in naturalsoil environment [18,19], but the underlying mechanisms bywhich ATZ binds to SOM remain largely unexplored. This is the firstresearch that demonstrates nucleophilic substitution could be animportant mechanism and sulfur-containing amino acids/peptidesplay a critical role as the nucleophile. We conceive this processwould diminish xenobiotic transport, bioavailability, and toxicity[33]. Understanding such mechanisms and governing factors is ofgreat importance to accurately predict the environmental behaviorof ATZ, making scientific environmental risk assessment possible.On the other hand, mechanistic understanding of ATZ sequestionmay catalyze novel ideas to mitigate ATZ contamination by takingadvantage of such processes in management and/or remediationprograms
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