the possibility exists that the acidophilic granulocytes of fish
fed the 10× PBDE diet produced a concentration of ROS that was
protective against L. anguillarum whereas those in fish fed the 1×
PBDE diet did not produce an ROS concentration that was protective
against the pathogen. An increased ROS response can come at a
price by overwhelming the fish’s antioxidant defense system which
can cause deleterious cellular effects such as lipid peroxidation and
protein oxidation