Pregnancy is a risk factor for the emergence or worsening of RLS. The prevalence of RLS in pregnancy is 26-32%. Severe RLS affects 15% of pregnant women. Symptoms usually appear or increase with advancing pregnancy. Using a validated RLS severity scale, severe RLS increased from 15% in the first trimester to nearly 35% in the third trimester. RLS typically resolves within the first month postpartum but can recur with subsequent pregnancies. Pre-pregnancy RLS patients typically return to baseline after delivery. Although RLS in pregnancy is highly prevalent, the disorder is frequently misdiagnosed or unrecognized by clinicians. RLS adversely effects maternal sleep duration and quality and daytime functioning. RLS, especially when severe, is associated with a risk of cardiovascular disease including hypertension, cerebrovascular disease, and coronary artery disease.