However, attention should be given in case of high doses , since their toxicity has not yet been fully elucidated. introduced Microtox® test as an evaluation tool for toxicity estimation of dietary plants extracts.
Microtox® analyzer uses the marine bioluminescent bacteria Vibrio fischeri as a reference test species and provides a sensitive, rapid, cost effective and reproducible method for the estimation of toxicity of toxicity of single compounds and mixtures of organic and inorganic compounds , biomaterials , without raising any ethical considerations were the first to propose its use to determine toxicity of herbal infusions and decoctions and evaluate interaction between water soluble and volatile compounds extracted by a non-polar organic solvent.