Erythromycin, an antibiotic commonly use in acne treatment
was selected to be a representative antibiotic in this study as most
of P. acnes isolates were susceptible to this drug. In this investigation,
we found no resistance to this antibiotic occurred in any of the
test isolates. However, resistance of P. acnes to erythromycin and
other antibiotics has been increasingly reported [9,25,26]. Consequently,
investigation on an active compound against P. acnes is
necessary. In this study, the ethanol extract demonstrated good
activity against all P. acnes isolates