and
administration 01 a 250 ml intravenous bolus 01 hypertonic saline solution (n = 35),
hypertonic saline plus dextran (n = 35), or isotonic saline solution (n = 35). This
inJusion u,'as immediately 1011owed by standard CT)'stalloid and blood replacement until
S),stolic pressure reached 100 mm Hg. Mean arterial pressure (MAP) was measured
every 5 minutes, and all intravenous inJusions were registered. Plasma volume
expansion was calculated from plasma protein concentration measurements. Patients
were 1011owed up throughout their hospital course, and results 01 treatment were
recorded.