In previous studies, we demonstrated the ability of suitable nanoparticles for very efficient removal of phenolic compounds similar to components of olive mill or winery wastewater [23]. Other studies [6, 24] presented a very effective pretreatment based on combinations of organoclay nanoparticles and crude clay, which changed the colloidal stability of winery and pickle industry effluents, reducing TSS and turbidity for several cycles by means of a two-step process: a first step performed with an organoclay and a second step performed by adding raw clay. In general, that process was similar to those used today in the industry: (a) a coagulation step, performed in the industry with cationic polymers, or with aluminum sulfate or other inorganic polycations (in the above report, the coagulant was based on an organoclay) and (b) a flocculation step performed in the industry with flocculants which are, in some cases, based on cationic or anionic polyacrylamide derivatives (in the above report, the flocculant was a raw clay mineral). The improvement proposed by Rytwo et al. [24] lays in the possibility of performing several cycles with the same amount of additives.