The diabetic rats were randomly divided into control group, model group(Mc), 100-cPoP group 100 mg/kg per body weight) mg/kg per body weight 200-cPOP group(200 mg/kg per body 400 CPOP group wei(400 mg/kg per body weight), and glyburide group(25 mg/kg per body weight On day 2 after the modeling, oral administration of the above described drugs was started on a for 28 days. Rats in the 100-CPOP 200 CPOP 400 CPOP, and glyburide groups were administered corresponding agents, and those in the control group(NC) and the model group(MC) were administered identical volumes of saline. Pre- and post- treatment general condition of the rats and changes in body weight were documented.