The ability of insulin to mediate tissue glucose uptake is
a critical step in maintaining glucose homeostasis and in
clearing the postprandial glucose load (Ginsberg et al.,
1975; Reaven, 1983). The insulin production is directly
proportional to the amount of sugar (carbohydrate)
consumed. The more sugar one consumes, the more
insulin the body will have to produce, but, the tiny
pancreatic beta cells were never designed to produce
this level of insulin. With a limited capacity to produce
insulin, a capacity that is more than sufficient to last a
lifetime under normal dietary conditions, the forced
over-production of insulin will eventually exhaust that
capacity and the cells will cease to operate