We found the PS-AM device was more effective in some cases than in others (Fig 4), possibly as a consequence of psychological tension causing variable degrees of autonomic nerve activity, which in turn would influence the peripheral circulation. The majority of subjects felt comfortable and sleepy when the PS-AM was running, suggesting that this method promotes relaxation. This study measured BF only in fine arteries near the dermal surface layer. To verify the effectiveness of the method, further studies are required to measure factors such as venous BF, cardiac output, and TPR.