Orange juice is a good source of vitamin C, an antioxidant that helps prevent and manage arthritis, cataracts, macular degeneration, and maintains healthy hair and skin. If fortified with calcium, orange juice may also help to maintain strong bones, reduce blood pressure, and alleviate PMS symptoms. If you have type 2 diabetes, it is best to avoid orange juice and other fruit juices because of the high sugar concentration. Because orange juice and other citrus juices are possible triggers for IBS and migraine headaches, avoid them if they are problematic for you.