The objective of the presented research was to identify the thermal environment and air quality conditions in an office room for two occupants equipped with personalized ventilation combined with chilled ceiling and to compare them with room conditions created by solutions used today such as mixing ventilation and combined system of chilled ceiling and mixing ventilation. An important part of the study was to evaluate whether mixing ventilation can be replaced by personalized ventilation as the only ventilation system in the rooms with chilled ceiling considering the environment at the workstation and in the occupied zone