Hand-foot-and-mouth disease may cause all of the following signs and symptoms or just some of them. They include:
Fever
Sore throat
Feeling of being unwell (malaise)
Painful, red, blister-like lesions on the tongue, gums and inside of the cheeks
A red rash, without itching but sometimes with blistering, on the palms, soles and sometimes the buttocks
Irritability in infants and toddlers
Loss of appetite