This study examines the potential profit of technical trading strategies like Moving average (MA), Relative Strength Index (RSI) & Moving Average Conversion Diversion (MACD) through dealing in S&P CNX Nifty. Researchers have used daily and monthly closing of S&P CNX Nifty for January 2001 to December 2011 period. The average buy-sell returns difference after trading costs for each strategy were compared to a buy and hold strategy. Researcher s found strong evidence of profitability by using RSI compared to other trading strategies in both long run and short run. In MA only SMA proved to better than Buy and Hold strategy while EMA could not prove its worth at all. MACD were equally good compared to B&H.