The objectives of our study were to determine the effects of the
SC-CO2 fluid extraction parameters (temperature ranging from 40
to 100 C, pressure ranging from 20 MPa to 40 MPa, and flow rates
ranging from 1.0 to 1.5 mL/min) on lycopene yield using response
surface methodology (RSM), a statistical technique that is favoured
for estimating the interaction of factors. Comparing yields, the
changing trends in antioxidant activities for the lycopene-rich extracts,
associated with the stability of lycopene, for various temperatures,
pressures, and flow rates in SC-CO2 fluid extraction
from tomato skin were also studied.