The temperature of the experimental animal room should be 22±3ºC. Although the
relative humidity should be at least 30% and preferably not exceed 70% other than during
room cleaning the aim should be 50-60%. Lighting should be artificial, the sequence being 12
hours light, 12 hours dark. For feeding, conventional laboratory diets may be used with an
unlimited supply of drinking water. Animals may be group-caged by dose, but the number of
animals per cage must not interfere with clear observations of each animal.