Biological Activities of Ganoderma
1. Anti-Androgenic activity
One of the major androgen mediated disease is benign prostate hyperplasia
(BPH), affecting almost 40% of men in age group of 50-60
years. 5 Alpha reductase enzymes cause it, which converts testosterone
to dihydrotesterosterone (DHT), which can play important role
in development of BPH. Naturally occurring 5 Alpha reductase inhibitors
can play important role in prevention of occurrence of BPH. In
an In vitro animal model study, Ganoderma lucidum extract showed
strongest 5-alpha reductase inhibitory activity among the 19 edible
and medicinal mushroom evaluated for their anti-androgenic activity.
(Fujita R et al 2005).
Anti-Hepatitis B activity