Diagnoses of chronic hypertension, prepregnancy diabetes, and gestational diabetes were more likely in
women with increasing prepregnancy maternal BMI ( p<0.0001). The odds of PIH also increased with BMI,
ranging from an odds ratio (OR) of 1.99 (95% confidence interval [CI] 1.73-2.31) for overweight women through
OR 4.26 (95% CI 3.37-5.38) for those with a BMI of 40 kg=m2. Other risk factors for PIH included chronic
hypertension (OR 6.57, 95% CI 5.43-7.95), nulliparity (OR 1.89, 95% CI 1.69-2.12), prepregnancy diabetes (OR
2.05, 95% CI 1.33-3.17), and gestational diabetes (OR 1.28, 95% CI 1.04-1.58). The presence of chronic hypertension
modified the association between obesity and PIH; for women with chronic hypertension, obesity was
not associated with PIH (adjusted OR [aOR] 1.39, 95% CI 0.77-2.50 for BMI 30–34.9; aOR 0.98, 95% CI 0.52-1.87
for BMI 35–39.9; and aOR 1.33, 95% CI 0.73-2.43 for BMI 40 kg=m2) compared with women with a BMI in the
normal range.
Conclusions: The risk of PIH rises with maternal prepregnancy BMI independent of other obesity-associated
comorbidity. Women with chronic hypertension carry the greatest risk of PIH but incur no obesity-associated
increase in risk.
Introduction
การแปล กรุณารอสักครู่..
