Such interactive effects play an important role in the cumulative response of a sample, which could be proven only by bioassay assessment.
These results confirm the fact that comet assay is a very sensitive and rapid technique for measuring DNA damage in individual cells. It is in fact more sensitive than short-term test using prokaryotic organisms (Ames test) and even yeast cells (Zimmermann test). This could be explained by the fact that bacteria do not posses internal metabolic activation enzyme system, responsible for xenobiotic metabolism and the addition of an exogenous system was not effective enough to