The developed analytical microsystems must be close to real-world demands
(the objective is to solve analytical problems). Just one of the main challenges
of analytical microsystems is dealing with thereal-world interface. That means
understanding the information needs of the client (identification of the problem
and its translation to an analytical level), which is a general challenge of any
analytical work. But, more important for microsystems, it also means ensuring
the representativeness of the results through an appropriate sampling plan and
a suitable method of analysis at the particular miniaturized level. This includes
achieving the selective and sensitivity requirements through sample treatment
and separation/detection