Under the optimal
chromatographic conditions, the adsorption capacity of the MIP-Flash column was determined as
107.3 mol/g, and in each process, 370.8 mg purified solanesol(98.4%) could be obtained from the extract
(20 mM, 40 ml) of tobacco leaves (14.7 g), and the yield of solanesol was 2.5% of the dry weight of tobacco
leaves. The results reported here confirm the feasibility to extract highly purified active ingredients
directly from natural products on a large scale by MIP-Flash chromatography.