For example, in mildly hypercholesterolemic men a daily dose of 50 mg of Orz, for 4 weeks, lowered total cholesterol, low-density lipoprotein (LDL) cholesterol, and LDL/high-density lipoprotein (HDL) cholesterol ratio by 6.3%, 10.5%, and 18.9%, respectively; whereas, increasing this dose to 800 mg/day did not enhance the pattern of lowering lipids