have search and tried everything i could find including including redownload winbox, delete %user%/appdata/mikrotik. Nothin has helped so far. I took a completely new router and on start up I could connect via the IP. I then clicked on "delete default scripte" and restarted winbox again i took a couple of minutes but winbox then found the router and listed the mac addr. and 0.0.0.0 for the IP. when trying to connect through the mac addr. the connection times out on port 20561.
I have two operating system on my PC and when I boot in the other windows operating system I have no problem. So I could solve it this way around, but it still bothers me, why it won't work with my normal windows installation.
I have also tried to disable the firewal / antivirus and this does not help either.