From a practice perspective, the study’s findings lend support for nurses and other healthcare professionals to be more vigilant in assessing and managing children’s symptom experiences. Successful care of children with cancer requires a comprehensive assessment; all symptoms warrant attention by nurses regardless of patients’ degree of distress. Therefore, all those caring for children with cancer must be cognizant of and consider all of the children’s symptom experiences. Even if children and families do not complain of any symptoms, nurses should inquire about the absence or presence of potential symptoms. Anticipatory guidance is key to symptom management. Nurses need to be careful and thorough in their assessments of children’s symptom experiences, especially considering the children in this study found that rating their symptoms on any type of self-assessment scale was not always helpful. Relying