In the present study, we aimed to investigate the feasibility
of the spray drying technique for the preparation of enteric
microparticles with V. cholerae inactivated strain prepared with
Eudragit® L30D-55 and FS30D as polymers. V. cholerae microencapsulation
might allow the development of novel vaccines, which
can be administered by mucosal routes but at the same time
preserving antigenicity of the bacteria. In addition, it would significantly
improve patient compliance by allowing immunization
to be achieved without needles.