Conclusions
T he results of this study demonstrated that hydrostatic pressurelevels of 550 to 650 MPa at pH 6.5 and RT are effective (> 5 DR)against cpe-positive C. perfringens type A vegetative cells but not
for spores. However, when hydrostatic pressure was combined with
high temperature, spores of P-cpe isolates and C. sporogenes strains
were significantly inactivated. Furthermore, when pH was lowered
to 4.75, significant inactivation was achieved on spores of C-cpe,
P-cpe, and C. sporogenes isolates