he treatment for pubic lice is usually with a 1% cream rinse of permethrin that is applied to the affected area and washed off after 10 minutes. Alternative treatments include pyrethrins with piperonyl butoxide applied for 10 minutes before washing off. None of these treatments should be used for involvement near the eyes because they can be very irritating. The patient's bedding and clothing should be machine-washed with hot water. All sexual partners within the preceding month should be treated for pubic lice and evaluated for other STDs.