These
results revealed significant dose-dependent inhibitory effects
of the carrageenan-induced paw edema at 1, 2, 3, 4, and hours after injection. The effect appeared 1 hour after
the injection and persisted all along the duration of the
experiment (5 hours). The peak anti-inflammatory effect of
the leaves extracts recorded with the dose of 200 mg/kg (BW)
at the fifth hour was 77.8 ± 2% for the chloroformic extract
and 68.1 ± 3.8% for the methanolic extract compared to the
standard drugs (ASA and Dexamethasone) which decreased
the paw edema by 62.9 ± 3.1% and 78.9 ± 3.3%, respectively,
at the fifth hour.