MHVA59
expressing the LCMV CD8 epitope gp33. We have selected
a recombinant MHV-A59 (RA59) expressing a foreign
CD8 T-cell epitope, gp33, derived from the glycoprotein (or
G protein) of LCMV. The gp33 epitope is expressed as a
fusion protein, sandwiched between a 9-amino-acid fragment
of the MHV ORF4a protein (37) and the EGFP (4)
ebrile, self-limited, biphasic disease called lymphocytic choriomeningitis (LCM), which is often complicated by aseptic meningitis. Infected but asymptomatic (carrier state) rodents, most commonly house mice, domestic mice, and hamsters, serve as reservoirs for LCMV.[1, 2] LCMV is most commonly transmitted via inhalation of infected excreta. Contamination of skin scratches is an important route of LCMV infection in pet handlers and laboratory technicians.
lymphocytic choriomeningitis virus