Background: Opisthorchiasis, caused by Opisthorchis viverrini, is of considerable public health importance in Southeast
Asia, particularly in Lao PDR and Thailand.
Objective: This study aims to analyze the risk areas for liver flukes in Surin province, Thailand using Geographic Information
Systems (GIS).
Material and Method: The 5 main factors (131 variables) were: (1) personal data (2) knowledge, attitude and practice, (3)
health service unit, (4) environmental data, and (5) climate data. The relationship between these main factors and liver fluke
infection was analyzed using multiple linear regression analysis. Potential surface analysis (PSA) with geographic information
systems (GIS) was performed to create maps displaying areas at risk for liver fluke infection in Surin province.
Results: The population density (148-169 pop/km2; X73), human attitude (