dna unwinding is facilitated by single-strand-specific dna-binding protens such as replication protein a (RP-A),which coat the ated byunwinding DNA third DNA synthesis is initiated on one or both templates. In cellular chromosomes and DNA viruses that do not encode their own DNA polymerase (e.g.,SV40,PyV,and PV), DNA polymerase-a:DNA primase complez esizes a short RAN-primedna nascent DNA chaim reserred to as an okazaki sragmgent the first okazaki fragment initiated on each template is extended contin uously by DNA polymerrase AND