Hydrogels are hydrophilic polymeric networks with the ability to absorb large amounts of water without losing their structure due to its chemical or physical crosslinks . Due to their high water content, similar to that of the hydrated body tissues, hydrogels show excellent biocom- patibility emerging as one of the most promising classes of biomaterials . Traditionally, methacrylate-based hydrogels obtained through photo-polymerization processes have been widely used in the biomedical field. Among them, primary amine-functionalized methacry- lates have generated considerable interest since their pri- mary amino offer the possibility of achieving a wide number of modification reactions. Particularly, 2-ami- noethyl methacrylate monomer (AEMA) has been fre- quently employed in biomedical applications. AEMA has been grafted onto poly-e-caprolactone films for tissue engi- neering applications , whereas poly (2-aminoethyl methacrylate) (pAEMA) has been studied as a potential DNA vaccine carrier or copolymerized for the design of protein resistant polymer coatings and oral drug deliv- ery applications.
Hydrogels are hydrophilic polymeric networks with the ability to absorb large amounts of water without losing their structure due to its chemical or physical crosslinks . Due to their high water content, similar to that of the hydrated body tissues, hydrogels show excellent biocom- patibility emerging as one of the most promising classes of biomaterials . Traditionally, methacrylate-based hydrogels obtained through photo-polymerization processes have been widely used in the biomedical field. Among them, primary amine-functionalized methacry- lates have generated considerable interest since their pri- mary amino offer the possibility of achieving a wide number of modification reactions. Particularly, 2-ami- noethyl methacrylate monomer (AEMA) has been fre- quently employed in biomedical applications. AEMA has been grafted onto poly-e-caprolactone films for tissue engi- neering applications , whereas poly (2-aminoethyl methacrylate) (pAEMA) has been studied as a potential DNA vaccine carrier or copolymerized for the design of protein resistant polymer coatings and oral drug deliv- ery applications.
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