TLJN treatment increased NT3 in the serum and ipsilateral
cerebral hemisphere of rats with MCAO
ELISA revealed that serum NT3 peaked 1 day after surgery
in MCAO model rats, but no significant differences were
observed between the model and normal groups throughout
the experiment (Figure 3A). In the brain, NT3 level was significantly
lower in the model group than in the normal group
7 days after surgery (P < 0.05) (Figure 3B). Rats that had
received TLJN showed significantly higher serum NT3 levels
than rats in the model group 7 days after MCAO (P < 0.05)
(Figure 3A). Rats that received XST had significantly lower
brain NT3 levels than those in the model group at 0.5 days
(P < 0.01) and 1 day (P < 0.05). At 3 days after MCAO, brain
NT3 level in the TLJN group was significantly greater than
that in the model and XST groups (P < 0.01)