The methanol extract of S.plagyophillum inhibited gram positive 12 mm for B.subtilis and 9 mm for S.aureus but not gram negative.Acetone, chloroform and ethyl acetate extracts, were only active against S.aureus,respectively caused 8 mm,6 mm and 9 mm zone of inhibition respectively.However,none of the extracts showed activity against B.subtilis, E.coli and P.aeruginosa.