in contrast,3D in vitro cell cultures reconstruct an environment much more similar to that observed in vivo.
Cells grown in 3D significantly differ from those grown in 2D conditions.
In addition to tissue regeneration applications,the 3D cultures allow for the in vitro reconstruction of biologically relevant disease models.
A 3D in vitro cancer model may be useful for studying cancer biology and for evaluating cellular responses to the pharmaceutical compounds in drug discovery applications