3.6. Acute toxicity
Stevia derivatives ST-GL and ST-AL were further evaluated for
their oral acute toxicity in male mice using a previously reported
method (Verma et al., 1994). The results indicated that the compounds
are nontoxic and well tolerated by experimental animals
up to 300 mg/kg. Moreover, these compounds were tested for their
toxicity through the parenteral route (Bekhit & Fahmy, 2003). The
results revealed that all test compounds were non-toxic up to
150 mg/kg.