Eradication therapy against H. pylori is fairly suc-
cessful in many cases, although sometimes treatment
failure occurs due to an antibiotic resistant strain.4,5)
Therefore it is important to seek a non-antibiotic
therapy that is not only highly effective but also non-
harmful to humans, and to examine the suppression of
chronic gastritis in high-risk areas including Japan. In
conclusion, our data suggest that it is likely to be able
to suppress oxidative DNA damage derived from
reactive oxygen and nitrogen species induced by
H. pylori infection and stress loading by treatment with
antioxidants.