5. GENETICTECHNIQUES USED
TO INCREASE SECONDARY
METABOLITE PRODUCTION
Genetic techniques used to increase secondary
metabolite productionare shown in table 1.These
compounds have a major effect on the health,
nutrition and economics of our society. The bestknown
are the antibiotics. These remarkable
groups of compounds form a heterogeneous
assemblage of biologically active molecules with
different structures and modes of action. They
attack virtually every type of microbial activity
such as DNA, RNA, and protein synthesis,
membrane function, electron transport, sporulation,