Diet: A diet low in ferment able diet fiber may affect ulcerrative colistic incidence. Breastfeeding: there have been conflicting reports of the protection of breastfeeding in the development of inflammatory bowel disease. One Italian study showed a potential protective effect. Several scientific studies have posted that Accutane is a possible trigger of Crohn's Disease and Ulcerative colitis in some individuals. three cases in the united States have gone to trial thus far, with all three resulting in multi-million dollar judgement against the makers of isotretinoin. there were an additional 425 case pending as of Autoimmune disease.