The prevalence of ความกังวลใจ (anxiety) in AD across the 25 studies reporting on 8,109 persons ranged from 12% to 70%. The overall pooled prevalence of ความกังวลใจ (anxiety) was 39% (95% CI 32–46%), with a substantial ความไม่เหมือนกัน (heterogeneity) (I2 = 97.7%, P < 0.05) across individual studies (Supplementary Fig. 10). Following we conducted meta-regression analyses, indicating that factors of evaluation method (p = 0.012) และ age (p = 0.012) could be explanations for some of the variance in the estimates (Table 1).