A distinction between osteochondrosis and osteochondritis dissecans lesions should be made, which can be a common source of confusion for physicians. Osteochondritis dissecans is an inflammatory condition of bone and overlying articular cartilage that affects the joints of patients with immature and mature skeletons alike. Either condition may present with activity-related pain, but osteochondritis dissecans may also cause joint catching and locking. Lesions from osteochondritis dissecans may or may not resolve with nonoperative treatment, whereas osteochondrosis eventually resolves when the growth plates have closed and skeletal maturity has been reached.