Objectives/Hypothesis: To evaluate nasal resistance in obese children with and without obstructive sleep apnea syndrome
(OSAS), study the correlation between nasal resistance and severity of OSAS using the apnea-hypopnea index (AHI),
and examine the association of gender and body mass index (BMI) with this measurement.
Study Design: Retrospective analysis.
Methods: Active anterior rhinomanometry was used to determine anterior nasal resistance (aNR) during wakefulness in
the supine position during tidal breathing. Thirty obese children with OSAS (aged 13.862.6 years, BMI z score 2.660.4)
and 32 matched obese controls (aged 13.662.3 years, BMI z score 2.460.4), were studied. Unpaired t tests and Spearman
correlation were performed.
Results: The OSAS group had significantly higher aNR than the non-OSAS group during inspiration (P5.012) and expiration
(P5.003). A significant correlation between inspiratory aNR and AHI was found for the OSAS group (r50.39, P5.04).
The aNR did not correlate with BMI z score or with either gender.
Conclusions: We noted a higher aNR in obese children with OSAS as compared to obese controls, and the aNR on inspiration
correlated significantly with AHI. These findings suggest that a causal or augmentative effect of high inspiratory aNR
may exist for obese children who exhibit OSAS.
Key Words: Active anterior rhinomanometry, obesity, obstructive sleep apnea syndrome.
Level of Evidence: 3b.
Objectives/Hypothesis: To evaluate nasal resistance in obese children with and without obstructive sleep apnea syndrome(OSAS), study the correlation between nasal resistance and severity of OSAS using the apnea-hypopnea index (AHI),and examine the association of gender and body mass index (BMI) with this measurement.Study Design: Retrospective analysis.Methods: Active anterior rhinomanometry was used to determine anterior nasal resistance (aNR) during wakefulness inthe supine position during tidal breathing. Thirty obese children with OSAS (aged 13.862.6 years, BMI z score 2.660.4)and 32 matched obese controls (aged 13.662.3 years, BMI z score 2.460.4), were studied. Unpaired t tests and Spearmancorrelation were performed.Results: The OSAS group had significantly higher aNR than the non-OSAS group during inspiration (P5.012) and expiration(P5.003). A significant correlation between inspiratory aNR and AHI was found for the OSAS group (r50.39, P5.04).The aNR did not correlate with BMI z score or with either gender.Conclusions: We noted a higher aNR in obese children with OSAS as compared to obese controls, and the aNR on inspirationcorrelated significantly with AHI. These findings suggest that a causal or augmentative effect of high inspiratory aNRmay exist for obese children who exhibit OSAS.Key Words: Active anterior rhinomanometry, obesity, obstructive sleep apnea syndrome.Level of Evidence: 3b.
การแปล กรุณารอสักครู่..