Herpes zoster is a common opportunistic infection among individuals with human immunodeficiency virus (HIV) infection. The incidence of herpes zoster among HIV-infected persons is about 30 cases per 1,000 person-years, which is approximately 15-fold higher than the incidence in an HIV-seronegative control population (3, 10). Following prompt treatment with a drug active against varicella-zoster virus (VZV), most cases of herpes zoster in HIV-infected persons resolve without sequelae. However, a wide variety of complications, including persistent skin lesions, disseminated VZV, encephalitis, and acute retinal necrosis have been reported and occur with increased frequency in individuals with CD4+-cell counts of