INTRODUCTION
Diabetes mellitus is a combination of heterogeneous
disorders commonly presenting with episodes of
hyperglycaemia and glucose intolerance, as a result of
lack of insulin , defective insulin action, or both (Sicree
et al., 2006). Such complications arise due to
derangements in the regulatory systems for storage and
mobilization of metabolic fuels, including the
catabolism and anabolism of carbohydrates, lipids and
proteins emanating from defective insulin secretion,
insulin action, or both (Shillitoe, 1988; Votey and
Peters, 2004).