MCCB raw data are presented in supplementary table 2. In all cases, BD patients had significantly better neurocognitive performance compared with SCZ patients. Investigation of correlations between global connectivity (ie, PC #1 scores) and neurocognitive tasks indicated that higher PC scores (ie, greater disconnectivity) were associated with worse cognitive performance across both patient groups (table 3); however, these effects were not statistically significant in either patient group when investigated separately. Seventeen of the 19 BD and 15 of the 18 SCZ patients completed BPRS assessments. BPRS scores were significantly higher in SCZ patients compared with BD patients (t = −3.05, df = 28.84, P = .005). BPRS scores correlated significantly with global connectivity (r = .37, df = 30, P = .035) such that lower connectivity was associated with higher BPRS scores. Subgroup analysis revealed that this relationship was, however, not significant among the SCZ or BD groups when examined separately. In addition, other measures (ie, HRSD, CARS-M) more sensitive to the mood and/or manic aspects of BD did not correlate significantly with connectivity strength.