To reduce the risks associated with RBC transfusion, new anticoagulants,
additive solutions, RBC membrane stabilizers, preservatives,
and bags have been developed [3, 4]. Despite these improvements,
a number of alterations in RBC concentrates have been described
and called ‘red cell storage lesions’. These include changes
in RBC shape and metabolism, in loss of carbohydrates, lipids and
proteins, in secretion and cell adhesion as well as in the oxygen
transpor