Our group recently found that CG repeats were refractory to nucleosome assembly, particularly when
the cytosines within the CG repeats were methylated [a modi-fication that facilitates/stabilizes Z-DNA structures (Wang et al.
unpublished data)].Thus, the impact of non-B DNA on chromatin structure may, in part, account for distal mutations (point mutations, small deletions, or insertions) seen hundreds of bps from the non-B DNA-forming sequences