You may also be at increased risk of ill effects from coffee if it contains caffeine and you take certain medications or herbal supplements. For instance, certain antibacterial medications can impede caffeine’s breakdown and increase the amount of time that its effects linger in your body. Additionally, you may experience heart palpitations, nausea and vomiting if you drink caffeinated coffee in conjunction with a bronchodilator called theophylline. You can reduce your risk of experiencing negative effects if you ask your pharmacist or doctor about whether consuming coffee could influence your medications.