These chains are then translocated across the plasma membrane to the extracellular matrix, where they assemble into crystalline microfibrils via interchain hydrogen bonding. Subsequent association with cuticular proteins and the formation of an ordered network of cross-linked fibers ensue [1,4–7]. Cuticular proteins are long recognized as serving many different roles, including chemical modification of the chitin microfibrils [8], remodeling of the chitin network [9], immunological defense [10], pigmentation [11–14] and cross-linking of chitin microfibrils in a process called sclerotization [15,16].